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Changes in blood glucose and lipids indicate a metabolic shift (405, 406, 410, 411) as there are reduced levels of acyl-carnitine and fatty acids (412), and amino acids from the urea cycle (187, 408)

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The letter went on to ask the FDA to increase enforcement over illegally imported obesity medications and other drugs by issuing warning letters, initiating civil enforcement actions and monitoring noncompliant online retailers and compounders selling unapproved [anti-obesity medications]. In a statement emailed to Healio, a spokesperson from HHS said, FDA is closely monitoring the compounding and distribution of GLP-1 drugs, including those marketed for weight loss

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